Drug Cures Osteoporosis in
Mice.
Results
Suggest Hope for Human Trials in the
Future.
A new study has concluded that an experimental drug which
inhibits serotonin in the gut has cured osteoporosis in
experimentally used mice and rats.
Prior studies have demonstrated that serotonin in the gut
(GI tract) suspends or blocks bone formation. The majority of
current pharmaceutical therapies for osteoporosis only prevent
the breakdown of bone. What they do not do is encourage new
bone growth.
Researchers who've discovered these
findings are naturally excited and encouraged at the results,
as they believe that this avenue of therapy provides a new
pathway for handling the disease.
I'm sure pharmaceutical companies are happy as well.
In this study, mice/rats were given small doses of the new
drug daily for six weeks. These particular rodents were
identified as having postmenopausal osteoporosis. The treatment
rendered was found to prevent the disease from full development
or achieving full resolution (cure) of the disease when
present.
Positive findings also show that while serotonin was
inhibited in the gut, levels remained as they should in the
brain. This signals that the drug should have less chance at
producing adverse side effects.
Going forward, researchers are hoping to extrapolate their
new findings and work toward solutions for humans, who have a
pronounced risk of contracting the disorder.
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